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CANCERS AND INDICATIONS ELIGIBLE FOR ENTRY IN THE NOPR
Cancers and indications that are reimbursable by Medicare are NOT
eligible for entry in the NOPR. Cancers and indications that are
specifically excluded for Medicare reimbursement are also not eligible
for entry in the NOPR.
| C |
= |
covered - Not eligible for entry in the NOPR |
| NC |
= |
non-covered nationally - Not eligible for entry in the NOPR |
| NOPR |
= |
covered only with entry in the NOPR |
| Lip, Oral Cavity, and Pharynx (140-149) |
C |
C |
| Esophagus (150) |
C |
C |
| Stomach (151) |
C |
NOPR |
| Small Intestine (152) (For carcinoid, see Neuroendocrine tumor below) |
C |
NOPR |
| Colon (153) and Rectum (154) (See below for anus) |
C |
C |
| Anus (154) (Considered distinct from rectum; see footnote 1) |
C |
NOPR1 |
| Liver and intrahepatic bile ducts (155) |
C |
NOPR |
| Gallbladder & extrahepatic bile ducts (156) |
C |
NOPR |
| Pancreas (157) |
C |
NOPR |
| Retroperitoneum and peritoneum (158) |
C |
NOPR |
| Nasal cavity, ear, and sinuses (160) |
C |
C |
| Larynx (161) |
C |
C |
| Lung, non-small cell (162) |
C |
C |
| Lung, small cell (162) |
C |
NOPR |
| Pleura (163) |
C |
NOPR |
| Thymus, heart, mediastinum (164) |
C |
NOPR |
| Bone/cartilage (170) |
C |
NOPR |
| Connective/other soft tissue (171) |
C |
NOPR |
| Melanoma of Skin (172) (Nasopharyngeal, ocular and vulvar/vaginal melanomas are coded based on those anatomic locations; PET not covered for regional nodal staging—see footnote 2) |
C / NC2 |
C |
| Non-melanoma of skin (173) |
C |
NOPR |
| Female breast (174) (PET not covered for diagnosis of breast masses or for axillary nodal staging—see footnotes 2 and 3) |
C / NC2,3 |
C |
| Male breast (175) (PET not covered for diagnosis of breast masses or for axillary nodal staging—see footnotes 2 and 3) |
C / NC2,3 |
C |
| Kaposi's sarcoma (176) |
C |
NOPR |
| Uterus, unspecified (179) |
C |
NOPR |
| Cervix (180) (PET covered for initial staging only with prior CT or MRI showing no extrapelvic metastatic disease—see footnote 4; otherwise NOPR) |
C / NOPR4 |
C |
| Placenta (181) |
C |
NOPR |
| Uterus, body (182) |
C |
NOPR |
| Ovary (183) |
C |
C |
| Uterine adnexa (183.2-183.9) |
C |
NOPR |
| Other and unspecified female genitalia (184) (Includes vulvar/vaginal melanoma) |
C |
NOPR |
| Prostate (185) |
NC |
NOPR |
| Testis (186) |
C |
NOPR |
| Penis and other male genitalia (187) |
C |
NOPR |
| Bladder (188) |
C |
NOPR |
| Kidney and other urinary tract (189) |
C |
NOPR |
| Eye (190) |
C |
NOPR |
| Primary Brain (191) |
C |
NOPR |
| Other and unspecified nervous system (192) |
C |
NOPR |
| Thyroid (193) (Covered for subsequent treatment strategy only if specific requirements met—see footnote 5; otherwise NOPR) |
C |
C / NOPR5 |
| Other endocrine glands and related structures(194) |
C |
NOPR |
| Metastatic cancer / unknown primary origin (196-199) |
C |
NOPR |
| Lymphoma (200-202) |
C |
C |
| Myeloma (203) |
C |
C |
| Leukemia (204-208) |
NOPR |
NOPR |
| Neuroendocrine tumor (209) |
C |
NOPR |
| Other or not listed |
C |
NOPR |
NOTES:
- Some Medicare contractors include anal cancer in their local coverage of "colorectal cancer"; for PET facilities served by those carriers, PET for subsequent treatment evaluation of anal cancer would be a covered indication.
- PET is non-covered for initial staging for axillary lymph nodes in patients with breast cancer and of regional lymph nodes in patients with melanoma, but is covered for detection of distant metastatic disease in high-risk patients with breast cancer or melanoma.
- PET is non-covered for "diagnosis" of breast cancer to evaluate a suspicious breast mass. However, PET is covered for initial treatment strategy evaluation of a patient with axillary nodal metastasis of unknown primary origin or in a patient with a paraneoplastic syndrome potentially caused by an occult breast cancer.
- Patient must have prior CT or MRI negative for extrapelvic metastatic disease for PET to qualify as a covered indication for initial treatment strategy evaluation. Patients who do not qualify for this covered indication (e.g., because CT or MRI was not done or because either CT or MRI showed extrapelvic metastatic disease) can be entered on NOPR.
- To qualify as a covered indication for subsequent treatment strategy evaluation, thyroid cancer must be of follicular cell origin and been previously treated by thyroidectomy and radioiodine ablation and the patient must have a serum thyroglobuilin > 10ng/ml and negative whole-body I-131 scan. Patients who do not qualify for this covered indication (e.g., because tumor is of other than follicular cell origin, the thryoglobulin is not elevated, or I-131 whole-body imaging was not performed or is positive) can be entered on NOPR.
IMPORTANT NOTE:
The scientific evidence concerning the clinical utility
of FDG-PET is generally less robust for cancers and indications that are
currently covered by Medicare only in the NOPR than for cancers and
indications that are currently covered without the requirement for clinical data submission
to the NOPR. For this reason, Medicare has conditioned coverage of
FDG-PET under the NOPR on the collection of clinical data. These data
will be used to help determine the clinical utility of FDG-PET for
conditionally covered cancers and indications. The billing physician
remains responsible for documenting medical necessity, which is required
for the coding and billing of both covered and NOPR-eligible PET
studies. Eligibility for the NOPR does not constitute a clinical
management recommendation for the use of PET for the conditionally
covered cancers and indications, by either the Medicare program or NOPR
investigators. Referring and interpreting physicians are thus advised
to refer to the published literature to better understand the potential
limitations of FDG-PET for NOPR-eligible uses.
GENERAL NOTE:
PET imaging of the brain with CPT code 78608 is covered for those cancers and
indications designated by “C” in the table above and is covered only under NOPR
for those cancers and indications indicated by “NOPR” in the table above. |
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